Zoloft and Lexapro side effects

SSRIs commonly cause early nausea, sleep changes, and sexual side effects that often improve over weeks. A provider can help manage side effects and adjust online.

Also called: SSRI side effects · starting Zoloft · Lexapro vs Zoloft

Medically reviewed by Dr. Ikechukwu Ogbu, MD
MD · Board-Certified, Internal Medicine · Last reviewed

Seek urgent care or the ER if you have:

  • Symptoms that are sudden, severe, or rapidly worsening
  • High fever (over 103°F / 39.4°C) that doesn't respond to treatment
  • Chest pain, trouble breathing, fainting, or confusion
  • Signs of dehydration — dizziness, dark urine, unable to keep fluids down
  • Symptoms in someone who is pregnant, immunocompromised, or over 65

What zoloft and lexapro side effects could be

The most common causes a clinician considers. This isn't a diagnosis — it's the differential a provider works through with you.

Depression

Commonly relevant when someone is researching "zoloft and lexapro side effects" — worth reviewing with a clinician who knows your history.

Anxiety

Commonly relevant when someone is researching "zoloft and lexapro side effects" — worth reviewing with a clinician who knows your history.

Panic disorder

Commonly relevant when someone is researching "zoloft and lexapro side effects" — worth reviewing with a clinician who knows your history.

Typical workup

What a clinician usually orders or asks about when someone presents with zoloft and lexapro side effects.

  • Focused history: timing, triggers, severity, and prior treatments related to "zoloft and lexapro side effects"
  • Targeted physical exam of the involved system
  • Rule-in / rule-out workup for the most likely causes: Depression, Anxiety, Panic disorder
  • Medication reconciliation, side-effect review, and any lab monitoring the drug requires

When to see a clinician

  • You're starting, stopping, or switching a medication and want a clinician's read on side effects
  • You've had a new symptom you think might be medication-related
  • You're due for the lab monitoring this medication requires
  • You want a second opinion on whether the medication is still the right choice

Common questions