Metformin side effects

GI upset is the most common metformin side effect; switching to extended-release usually helps. A provider can adjust dosing and monitor labs online.

Also called: metformin nausea · metformin diarrhea · extended release metformin

Medically reviewed by Dr. Ikechukwu Ogbu, MD
MD · Board-Certified, Internal Medicine · Last reviewed

Where this comes up clinically

Conditions this topic is usually discussed alongside. Not a recommendation to start, stop, or change any medication.

Type 2 diabetes

Commonly relevant for people looking into "Metformin side effects" — worth reviewing with a clinician who knows your history.

Prediabetes

Commonly relevant for people looking into "Metformin side effects" — worth reviewing with a clinician who knows your history.

PCOS

Commonly relevant for people looking into "Metformin side effects" — worth reviewing with a clinician who knows your history.

When to see a clinician

  • You're starting, stopping, or switching a medication and want a clinician's read on side effects
  • You've had a new symptom you think might be medication-related
  • You're due for the lab monitoring this medication requires
  • You want a second opinion on whether the medication is still the right choice

Medications commonly used

Common questions