Low testosterone / TRT evaluation

Blood testing and referral to appropriate specialist

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Low testosterone / TRT evaluation
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Medically reviewed by Dr. Ikechukwu Ogbu, MD
MD · Board-Certified, Internal Medicine · Last reviewed

About Low testosterone / TRT evaluation

Evaluation for low testosterone begins with morning fasting total testosterone confirmed on two separate occasions, plus LH, FSH, prolactin, SHBG hemoglobin, lipids, and PSA in older men. True hypogonadism requires both biochemical confirmation and clinical symptoms — low libido, fatigue, decreased morning erections, mood changes. Reversible causes (obesity, sleep apnea, alcohol, opioids) should be addressed first. Testosterone replacement is appropriate for confirmed hypogonadism and is contraindicated in untreated prostate cancer, severe untreated sleep apnea, and active fertility plans, since exogenous testosterone suppresses sperm production.

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